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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PREPL
All Species:
14.55
Human Site:
Y38
Identified Species:
29.09
UniProt:
Q4J6C6
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q4J6C6
NP_001035844.1
727
83927
Y38
Y
N
F
A
D
H
C
Y
N
R
I
K
L
K
K
Chimpanzee
Pan troglodytes
XP_001144400
727
83999
Y38
Y
N
F
A
D
H
Y
Y
N
R
I
K
L
K
K
Rhesus Macaque
Macaca mulatta
XP_001111959
727
83985
Y38
Y
N
F
A
D
H
Y
Y
N
R
I
K
L
K
K
Dog
Lupus familis
XP_531803
727
83861
Y38
C
N
F
A
D
H
Y
Y
N
R
I
K
L
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8C167
725
83176
L41
P
Y
Y
S
R
V
R
L
K
K
Y
H
L
T
K
Rat
Rattus norvegicus
Q5HZA6
726
83463
L46
L
R
L
K
N
Y
R
L
T
K
C
L
Q
N
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521562
342
37329
Chicken
Gallus gallus
Q5ZKL5
732
84295
G56
C
N
S
A
V
P
P
G
R
I
L
S
W
R
L
Frog
Xenopus laevis
Q32N48
707
80150
Y39
F
S
A
G
I
T
R
Y
S
R
S
T
V
Y
R
Zebra Danio
Brachydanio rerio
NP_001139088
692
78210
L41
Y
S
E
G
P
T
E
L
S
K
A
Q
L
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780381
720
80994
A39
E
L
L
Q
Y
I
K
A
E
N
N
F
S
E
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001151599
784
87028
A52
K
V
P
F
N
V
S
A
H
G
R
S
W
S
D
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99
96.1
N.A.
90.9
90.3
N.A.
26.5
47.5
42
37.9
N.A.
N.A.
N.A.
N.A.
29.3
Protein Similarity:
100
99.7
99.5
98.3
N.A.
95
94.7
N.A.
34.5
66.6
61.4
54.8
N.A.
N.A.
N.A.
N.A.
51.4
P-Site Identity:
100
93.3
93.3
86.6
N.A.
13.3
6.6
N.A.
0
13.3
13.3
20
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
93.3
93.3
86.6
N.A.
33.3
26.6
N.A.
0
26.6
46.6
53.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
26.7
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
46.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
42
0
0
0
17
0
0
9
0
0
0
0
% A
% Cys:
17
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% C
% Asp:
0
0
0
0
34
0
0
0
0
0
0
0
0
0
9
% D
% Glu:
9
0
9
0
0
0
9
0
9
0
0
0
0
9
0
% E
% Phe:
9
0
34
9
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
0
0
17
0
0
0
9
0
9
0
0
0
0
0
% G
% His:
0
0
0
0
0
34
0
0
9
0
0
9
0
0
0
% H
% Ile:
0
0
0
0
9
9
0
0
0
9
34
0
0
0
0
% I
% Lys:
9
0
0
9
0
0
9
0
9
25
0
34
0
34
59
% K
% Leu:
9
9
17
0
0
0
0
25
0
0
9
9
50
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
42
0
0
17
0
0
0
34
9
9
0
0
9
0
% N
% Pro:
9
0
9
0
9
9
9
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
0
9
9
9
9
% Q
% Arg:
0
9
0
0
9
0
25
0
9
42
9
0
0
9
9
% R
% Ser:
0
17
9
9
0
0
9
0
17
0
9
17
9
9
0
% S
% Thr:
0
0
0
0
0
17
0
0
9
0
0
9
0
9
0
% T
% Val:
0
9
0
0
9
17
0
0
0
0
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% W
% Tyr:
34
9
9
0
9
9
25
42
0
0
9
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _